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Ku-70 Polyclonal Antibody, 100ul[BT-AP04896] Electrophoresis & Labeling The encoded protein is localized

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Ku-70 Polyclonal Antibody, 100ul[BT-AP04896] Electrophoresis & Labeling The encoded protein is localizedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

The encoded protein is localized to the nucleolus where it functions in chromatin remodeling and as an inhibitor of cell-cycle progression

It was reported to have phosphorylation-dependent DNA-primase activity

dynorphin A and other peptide hormones

The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein

also called triple-A syndrome or Allgrove syndrome

Ku-70 Polyclonal Antibody, 100ul[BT-AP04896] Electrophoresis & Labeling The encoded protein is localizedThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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