TF2H3 Rabbit Polyclonal Antibody, 20ul Virus Packaging Functional studies indicate that this

Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression

and thus plays a role in the cell response to environmental stresses

It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis

This gene thus plays a role in both cell-cycle and epigenetic regulation

including the products of tumor suppressor genes and dominant protooncogenes

TF2H3 Rabbit Polyclonal Antibody, 20ul Virus Packaging Functional studies indicate that thisThis gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14.