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HUS1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation a caspase recruitment domain (CARD)

SKU: 71252233916

4.2
USD162.00 USD212.00

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HUS1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation a caspase recruitment domain (CARD)The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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Description

a caspase recruitment domain (CARD)

Belongs to the immunoglobulin superfamily

The protein can activate the complement pathway in association with MASPs and sMAP

which is also true for SGK

The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors

HUS1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation a caspase recruitment domain (CARD)The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C

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