AMNLS Polyclonal Antibody, 20ul Human Genome Knockout Libraries CEP76 (centrosomal protein 76) encodes

CEP76 (centrosomal protein 76) encodes a centrosomal protein which regulates centriole amplification by limiting centriole duplication to once per cell cycle

HIST1H2BA is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

The activation peptides of aspartic proteinases function as inhibitors of the protease active site

When overexpressed in mammalian cells

AMNLS Polyclonal Antibody, 20ul Human Genome Knockout Libraries CEP76 (centrosomal protein 76) encodesThe protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short