Rat Dipeptidase 2, DPEP2 ELISA Kit, 96T Human Genome Knockout Libraries host homeostasis

host homeostasis

Isoform 2 is expressed in liver

It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family

Regulates the composition of intestinal microbiota and immune tolerance by inducing antimicrobial proteins that specifically control the growth of commensal Firmicutes and Bacteroidetes (PubMed: 29915298)

and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703)

Rat Dipeptidase 2, DPEP2 ELISA Kit, 96T Human Genome Knockout Libraries host homeostasisDipeptidase that hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4). Does not hydrolyze cystinyl bis glycine. Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF kappa B inflammatory signaling pathway.