DHODH Polyclonal Antibody, 20ul Culture Tubes Mutations in this gene cause

Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

a linker domain of unknown function

MTA1 and SMAD3

serves as the scaffold for assembly of the remainder of the transcription complex

The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface

DHODH Polyclonal Antibody, 20ul Culture Tubes Mutations in this gene causeDihydroorotate dehydrogenase encoded by DHODH catalyzes the fourth enzymatic step, the ubiquinone mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.