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Ezrin(Phospho Tyr478) Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing The encoded protein may bind

SKU: 6842051442

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Ezrin(Phospho Tyr478) Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing The encoded protein may bindThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been

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Description

The encoded protein may bind single-stranded DNA

tissue specificity:Strongly expressed in kidney and to a lower extent in liver

the encoded protein binds to the ER stress response element

It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate

Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types

Ezrin(Phospho Tyr478) Polyclonal Antibody, 100ul Hybridoma Antibody Sequencing The encoded protein may bindThe cytoplasmic peripheral membrane protein encoded by this gene functions as a protein tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been

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