SP130 Polyclonal Antibody, 20ul Pathway and Network Analysis The encoded protein tranduces signals

The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex

also referred to as Nettleship-Falls type ocular albinism

and play a role in spindle formation during mitosis

This gene encodes the largest non-ATPase subunit of the 19S regulator lid| which is responsible for substrate recognition and binding

Several alternatively spliced transcript variants encoding three distinct isoforms have been reported

SP130 Polyclonal Antibody, 20ul Pathway and Network Analysis The encoded protein tranduces signalsSAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241) dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003