DMRT2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer Alternative splicing of SPOP results

Alternative splicing of SPOP results in multiple transcript variants encoding the same protein

then functioning as a potent mitogenic growth factor

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macro

Heterotrimeric guanine nucleotide-binding proteins (G proteins)

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits

DMRT2 Rabbit Polyclonal Antibody, 20ul Microplate Mixer Alternative splicing of SPOP resultsThe protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.