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U-PAR Rabbit Polyclonal Antibody, 20ul Antibodies Two isoforms of MAP-9 are

SKU: 6792003874

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U-PAR Rabbit Polyclonal Antibody, 20ul Antibodies Two isoforms of MAP-9 areActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.

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Description

Two isoforms of MAP-9 are produced due to alternative splicing events

Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection

This intronless gene may be a pseudogene (PMID:11450850)

T and B cells

The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure

U-PAR Rabbit Polyclonal Antibody, 20ul Antibodies Two isoforms of MAP-9 areActs as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis independent signal transduction activation effects of U PA. It is subject to negative feedback regulation by U PA which cleaves it into an inactive form. Contains 3 UPAR Ly6 domains. subunit: Monomer (Probable). Interacts with MRC2.

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