PDH-E1 Alpha Monoclonal Antibody, 50ul Cell Biology Take risks and achieve greatness

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MIM 180660) and several general initiation factors (summarized by DeJong and Roeder

As in yeast

Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments

This protein preferentially induces apoptosis in transformed and tumor cells

PDH-E1 Alpha Monoclonal Antibody, 50ul Cell Biology Take risks and achieve greatnessThe pyruvate dehydrogenase (PDH) complex is a nuclear encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme