EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression The protein (ataxin 2) encoded

The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus

Multiple alternatively spliced variants encoding different isoforms have been described

Two transcript variants encoding the same protein have been found for KRT18

which is necessary for protein synthesis

a gene expressed in the head and limbs of the developing fruit fly

EpoR Polyclonal Antibody, 20ul[BT-AP03025] Insect Expression The protein (ataxin 2) encodedEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce