MAPKAPK-2(Phospho-Thr334) Rabbit Polyclonal Antibody, 20ul Immunoassays Interaction with PDCD1 inhibits T-cell

Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression

PTM:Phosphorylation on Ser-1026

and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway

MAPKAPK-2(Phospho-Thr334) Rabbit Polyclonal Antibody, 20ul Immunoassays Interaction with PDCD1 inhibits T-cellThis gene encodes a member of the Ser Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase this kinase is known to be involved in many cellular processes including stress and inflammatory responses nuclear export gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript