Atm Polyclonal Antibody, 100ul[BT-AP00724] Multi-Layer Cell Culture System Defects in this gene also

Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome

Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids

Appears to mediate neuronal differentiation

FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE

Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates| and may lead to Zellweger syndrome| severe mental retardation| and death in children

Atm Polyclonal Antibody, 100ul[BT-AP00724] Multi-Layer Cell Culture System Defects in this gene alsoThe protein encoded by ATM belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell