TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis Defects in this gene lead

Defects in this gene lead to many pathophysiologic problems

Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions

The protein includes an N-terminal SCAN domain| and seven C2H2-type zinc finger motifs

and a widespread distribution in the brain

Contains 2 PLD phosphodiesterase domains

TERT(Phospho Ser227) Polyclonal Antibody, 20ul DNA Oligo Synthesis Defects in this gene leadTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.