Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers The protein (tumor necrosis factor

The protein (tumor necrosis factor superfamily member 9) encoded by TNFSF9 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family

The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus

A 117 kb microdeletion at the 5' end of the HOXD gene cluster| which includes this gene and the HOXD9-HOXD13 genes| causes synpolydactyly| a dominantly inherited disease resulting in limb malformation

the activity of the encoded protein depends on the protein binding partner

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers The protein (tumor necrosis factor