TEKT1 Rabbit Polyclonal Antibody, 100ul Variant Libraries Overexpression of Baff in mice

Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE)

Mutations in DCLRE1C can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome

which suggests a related but distinct role of this protein

This gene encodes a member of the myosin superfamily

The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus

TEKT1 Rabbit Polyclonal Antibody, 100ul Variant Libraries Overexpression of Baff in miceThis gene product belongs to the tektin family of proteins. Tektins comprise a family of filament forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules indicating that it may play a role in spermatogenesis.