SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy The protein is thought to

The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

The protein encoded by MED14 (mediator complex subunit 14) is a subunit of the CRSP (cofactor required for SP1 activation) complex

The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1

This protein can interact with proliferating cell nuclear antigen

SREBP-1 Polyclonal Antibody, 50ul[BT-AP08552] Apoptosis & Autophagy The protein is thought toSREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by