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Bcr Polyclonal Antibody, 20ul[BT-AP00878] sgRNA Library Construction encoding different isoforms
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PLN141.20
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Bcr Polyclonal Antibody, 20ul[BT-AP00878] sgRNA Library Construction encoding different isoformsA reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR ABL fusion protein has been extensively studied, the
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