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IκB-alpha(phospho Ser32/S36) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging The Reg gene family is

SKU: 66141546207

4.3
PLN97.20 PLN128.20

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IκB-alpha(phospho Ser32/S36) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging The Reg gene family isThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

The Reg gene family is a multigene family grouped into four subclasses

Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability

This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis

These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms

it may function in fertility

IκB-alpha(phospho Ser32/S36) Polyclonal Antibody, 20ul Adeno-associated Virus Packaging The Reg gene family isThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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