Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that it may have

suggesting that it may have a role in transcription regulation

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suggesting that this kinase may serve as an intermediate in the response to cellular stress

This gene encodes a member of the Rho family of small GTPases

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that it may haveMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.