PTGR2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes Studies in the knockout mice

Studies in the knockout mice suggested the roles of CDKN2C in regulating spermatogenesis

ubiquitination targets the protein for rapid degradation via the ubiquitin system

A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation

Polymorphisms in this gene may be associated with osteoarthritis in human patients

The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site

PTGR2 Polyclonal Antibody, 100ul Micro Centrifuge Tubes Studies in the knockout micePTGR2 encodes an enzyme involved in the metabolism of prostaglandins. Prostaglandin reductase 2 catalyzes the NADPH dependent conversion of 15 keto prostaglandin E2 to 15 keto 13,14 dihydro prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator activated receptor. Alternative splicing results in multiple transcript variants.