HMG-14 Polyclonal Antibody, 50ul Centrifugal Filter Multiple isoforms of CaMKV exist

Multiple isoforms of CaMKV exist due to alternative splicing events

nvolved in the cornified cell envelope formation

The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling

Represses the transcriptional activator activity of BRCA1 (PubMed: 20160719)

and they have intrinsic GTPase activity

HMG-14 Polyclonal Antibody, 50ul Centrifugal Filter Multiple isoforms of CaMKV existThe high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.