UBE2T Polyclonal Antibody, 100ul Biochemical Reagents suggesting an important role in

suggesting an important role in p53/TP53 stress response such as DNA damage

Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates

The isoforms

Dok-6 is highly expressed in the developing central nervous system

UBE2T Polyclonal Antibody, 100ul Biochemical Reagents suggesting an important role inUbiquitin conjugating enzyme E2 T encoded by UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Defects in this gene have been associated with Fanconi anemia of complementation group T. Two transcript variants encoding different isoforms have been found for this gene.