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APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a member

SKU: 64848674863

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APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a memberAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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Description

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases)

This enzyme

An important paralog of this gene is HAP1

Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble

It is a C-type lectin with mannose binding specificity

APLP-1 Polyclonal Antibody, 100ul Thermal Control This gene is a memberAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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