STRUM Rabbit Polyclonal Antibody, 50ul Protein Research Mutations in the alpha or

Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses

This protein is expressed by T cells and macrophages

tissue specificity:Expressed in many tissues

Belongs to the S-100 family

The protein encoded by this gene belongs to the DMRT gene family| sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C

STRUM Rabbit Polyclonal Antibody, 50ul Protein Research Mutations in the alpha orThis gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower