PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis which are binding partners to

which are binding partners to the RAB5 small GTPases

This locus encodes a LEM domain-containing protein

and thus may transduce signals for cell survival and proliferation

|PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes

Three alternatively spliced transcript variants that encode different protein isoforms have been described

PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis which are binding partners toPresenilins which are components of the gamma secretase protein complex are required for intramembranous processing of some type I transmembrane proteins such as the Notch proteins and the beta amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta amyloid precursor protein generates neurotoxic amyloid beta peptides the major component of senile plaques associated with