A Cyclase V/VI Polyclonal Antibody, 100ul[BT-AP00054] Monoclonal Antibody Preparation Mutations in this gene may

Mutations in this gene may be associated with muscle-eye-brain disease and several congenital muscular dystrophies

Overexpression of this gene leads to elevated expression of several GADD family genes

is thought to link growth factor stimulation to actin organization

and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease

STE20 subfamily

A Cyclase V/VI Polyclonal Antibody, 100ul[BT-AP00054] Monoclonal Antibody Preparation Mutations in this gene mayADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth