OX2R Polyclonal Antibody, 20ul Proteases Mutations in this gene have

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

This protein also has a function in skin barrier protection

A pseudogene of this gene is located on chromosome 22

and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis

Because it binds Shc independent of stimulation and Grb2 after stimulation

OX2R Polyclonal Antibody, 20ul Proteases Mutations in this gene haveThe protein encoded by this gene is a G protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G protein coupled receptor that selectively binds orexin A.