Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIP

The protein encoded by VIP (vasoactive intestinal peptide) belongs to the glucagon family

Alternate splice variants have been described but their full length sequences have not been determined

and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B

It interacts in a complex with chromatin modifying factors

RUNX proteins form a heterodimeric complex with CBFβ which confers increased DNA binding and stability to the complex

Sgo1 Polyclonal Antibody, 100ul Fluorescent Staining The protein encoded by VIPShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found