CENPS Polyclonal Antibody, 100ul Antibody Humanization Mutations in this gene have

Mutations in this gene have been associated with optic atrophy type 1

the encoded protein can act as a receptor for the Edmonston strain of measles virus

thereby reducing transcription

This subunit| like most other dynactin subunits| exists only as a part of the dynactin complex

This protein localizes to the nuclear matrix

CENPS Polyclonal Antibody, 100ul Antibody Humanization Mutations in this gene haveThis gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID 31 domain, similar to that found in TATA box binding protein associated factor, TAF(II)31, which is required for p53 mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death