Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment The importance of the iron

The importance of the iron binding function has not yet been identified

The protein encoded by DDR1 (discoidin domain receptor tyrosine kinase 1) belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain

The encoded protein (distal-less homeobox 5) may play a role in bone development and fracture healing

postaxial polydactyly types A1 and B

a member of the short-chain dehydrogenase/reductase superfamily

Raf-1 Polyclonal Antibody, 50ul[BT-AP13535] In vitro Assessment The importance of the ironThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.