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PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07144] DNA Oligo Synthesis This gene was mapped to

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PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07144] DNA Oligo Synthesis This gene was mapped toPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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Description

This gene was mapped to 17q21

Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues

This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides

This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells

This gene encodes a member of the histidine triad (HIT) superfamily

PI 3-kinase p85 Alpha Polyclonal Antibody, 100ul[BT-AP07144] DNA Oligo Synthesis This gene was mapped toPhosphatidylinositol 3 kinase phosphorylates the inositol ring of phosphatidylinositol at the 3 prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. PIK3R1 encodes the 85 kD regulatory subunit. Phosphatidylinositol 3 kinase plays an important role in the metabolic actions of insulin, and a mutation in PIK3R1 has been associated with insulin resistance. Alternative splicing of PIK3R1

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