Cdc37(Phospho Ser13) Polyclonal Antibody, 100ul Polyclonal Antibody Preparation as well as in T

as well as in T cell-dependent B cell proliferation and differentiation

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family

Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM)

and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis

Two alternatively spliced transcript variants encoding different isoforms have been found for this gene

Cdc37(Phospho Ser13) Polyclonal Antibody, 100ul Polyclonal Antibody Preparation as well as in TThe protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF 1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.