PLCB4 Polyclonal Antibody, 20ul Electrophoresis & Labeling The major isoform of this

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains

Heterozygous loss-of-function mutations in KLF1 result in the dominant In (Lu) blood phenotype

Dimerization is required for the binding of poly-ubiquitin

And beta I has an allelic variant named alpha II

PLCB4 Polyclonal Antibody, 20ul Electrophoresis & Labeling The major isoform of thisThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene.