SYGP1 Polyclonal Antibody, 100ul Pipette Filler Diacylglycerol kinases (DGKs) are regulators

Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes

This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

Unlike monomeric members of this protein family| this protein exists as a homodimer and forms stable dimers with DNA elements

a single fibronectin type III domain

possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex

SYGP1 Polyclonal Antibody, 100ul Pipette Filler Diacylglycerol kinases (DGKs) are regulatorsThe protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).