IGFBP6 Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in COL18A1 are associated

Mutations in COL18A1 are associated with Knobloch syndrome

and learning disabilities

3 that encodes a transmembrane G protein-coupled receptor

Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles

Eight alternatively spliced transcript variants have been described

IGFBP6 Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in COL18A1 are associatedIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.