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Phospho-Akt (S473) Polyclonal Antibody, 100ul[BT-PHS00006] In vitro Assessment Duplication of a regulatory region

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Phospho-Akt (S473) Polyclonal Antibody, 100ul[BT-PHS00006] In vitro Assessment Duplication of a regulatory regionThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients

GSK3A encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase

The coagulation process initiates with the formation of a factor VIIa-TF complex

or peptide YY (PYY)

and may be involved in inflammation and immune regulation

Phospho-Akt (S473) Polyclonal Antibody, 100ul[BT-PHS00006] In vitro Assessment Duplication of a regulatory regionThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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