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Filamin 1(Phospho Ser2152) Polyclonal Antibody, 50ul Insect Expression In case of HIV-1 infection|

SKU: 59780991009

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SEK185.00 SEK221.00

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Filamin 1(Phospho Ser2152) Polyclonal Antibody, 50ul Insect Expression In case of HIV-1 infection|The protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias

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Description

In case of HIV-1 infection| the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

Required for CDT1 proteolysis in response to DNA damage through the CUL4-DDB1 E3 ubiquitin-protein ligase

The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location

This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators

RPL27A encodes a ribosomal protein that is a component of the 60S subunit

Filamin 1(Phospho Ser2152) Polyclonal Antibody, 50ul Insect Expression In case of HIV-1 infection|The protein encoded by this gene is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias

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