Parkin Polyclonal Antibody, 20ul Cell Culture Plates This growth factor lacks the

This growth factor lacks the N-terminal signal sequence present in most of the FGF family members

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It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain

with variations due to deletions

Parkin Polyclonal Antibody, 20ul Cell Culture Plates This growth factor lacks theThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have