p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma enhancing the DNA-binding activity of

enhancing the DNA-binding activity of serum response factor

Paired box transcription factors are important regulators in early development

Interacts with MAFB

and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A

p57(Phospho Thr310) Polyclonal Antibody, 50ul Plasma enhancing the DNA-binding activity ofThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.