TNKS2 Polyclonal Antibody, 50ul Petri Dishes The 3' coding sequence of

The 3' coding sequence of UBXN11 contains a polymoprhic region of 24 nt tandem repeats

1| a region reduced to homozygosity in small-cell lung cancer (SCLC)| and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors

The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function

also known as COLFI domain

alternative products:A number of isoforms

TNKS2 Polyclonal Antibody, 50ul Petri Dishes The 3' coding sequence ofCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4 GLUT4 vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM: ADP ribosylated ( auto).,Contains 1 PARP catalytic domain.,Contains 1 SAM (sterile alpha motif) domain.,Contains 15 ANK repeats.,subcellular