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AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes differentiation and migration by binding

SKU: 58626917343

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AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes differentiation and migration by bindingThis gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta 1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The

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Description

differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells

Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1)

|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level)

Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia

Isoform 2 and isoform 3 are poorly detected in heart

AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes differentiation and migration by bindingThis gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta 1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The

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