MEK Kinase-1 Polyclonal Antibody, 20ul[BT-AP05333] Site-directed Mutagenesis The subcellular localization and function

The subcellular localization and function of this protein are modulated by post-translational modifications

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Component of the little elongation complex (LEC)

which is a regulator of light-mediated signal transduction in plant cells

resulting in the inhibition of TRAF6 NF-kappa-B activation

MEK Kinase-1 Polyclonal Antibody, 20ul[BT-AP05333] Site-directed Mutagenesis The subcellular localization and functionThe protein encoded by MAP3K1 (mitogen activated protein kinase kinase kinase 1) is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N