Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 20ul[BT-AP05347] ROS/Nitric Oxide Detection the C-terminal kinase domain binds

the C-terminal kinase domain binds to its own N-terminal region

Several alternatively spliced transcript variants encoding different isoforms have been identified

such as Gilson

This protein can also bind to other related surface molecules that are expressed on activated T

Contains 1 CNH domain

Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 20ul[BT-AP05347] ROS/Nitric Oxide Detection the C-terminal kinase domain bindsThis gene encodes a member of the tyrosine kinase and more specifically the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such it may play a role in anti viral immunity. A mutation in this gene has been