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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin protein

SKU: 58301736285

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Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin proteinSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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Description

MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase

Alternative coreceptor with CD4 for HIV-1 infection

TACC3 encodes a member of the transforming acidic colied-coil protein family

MARK proteins phosphorylate MAPs within their microtubule binding domains

Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment MIB1 (mindbomb E3 ubiquitin proteinSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response

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