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EF-1Beta Polyclonal Antibody, 50ul Pipette Filler DAD1| the defender against apoptotic

SKU: 58120173570

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EF-1Beta Polyclonal Antibody, 50ul Pipette Filler DAD1| the defender against apoptoticEEF1B2 encodes a translation elongation factor. Elongation factor 1 beta is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR.

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Description

DAD1| the defender against apoptotic cell death| was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line

The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes

Growth factor receptor-bound protein 10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

it can associate with transglutaminase 3

Also| it is thought that the presenilins are involved in the cleavage of the Notch receptor such that| they either directly regulate gamma-secretase activity| or themselves act are protease enzymes

EF-1Beta Polyclonal Antibody, 50ul Pipette Filler DAD1| the defender against apoptoticEEF1B2 encodes a translation elongation factor. Elongation factor 1 beta is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR.

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