CD172b Polyclonal Antibody, 100ul Lysosome An important paralog of this

An important paralog of this gene is RPA4

The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production

Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome

a variable cytoplasmic loop

Interacts with phosphorylated proteins ZAP70

CD172b Polyclonal Antibody, 100ul Lysosome An important paralog of thisSignal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase coupled signaling processes. This protein was found to interact with TYROBP DAP12, a protein bearing immunoreceptor tyrosine based activation motifs.