Lamin A/C(Phospho Ser392) Polyclonal Antibody, 100ul Nucleic Acid Amplification Expression of the mouse homolog

Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling

and an intracellular domain consisting of multiple

This protein is reported to interact with other CARD domain containing proteins including CARD9

Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling

Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins

Lamin A/C(Phospho Ser392) Polyclonal Antibody, 100ul Nucleic Acid Amplification Expression of the mouse homologThe nuclear lamina consists of a two dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B.