MED11 Polyclonal Antibody, 50ul Drying & Desiccation Modulates signaling via SHC1 by

Modulates signaling via SHC1 by competing for a common binding site on NTRK1

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression

This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal

This gene uses alternative transcription start sites

Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding

MED11 Polyclonal Antibody, 50ul Drying & Desiccation Modulates signaling via SHC1 byMED11 is a component of the Mediator complex, which is a coactivator for DNA binding factors that activate transcription via RNA polymerase II (Sato et al., 2003